Duplicated gallbladder

Images

Figure 1

Figure 2

Figure 3A

Figure 3B

Figure 4A

Figure 4B


Clinical History:

62 year old male presents with right lower quadrant pain


Findings:

Figure 1: Grey scale ultrasound scan of gallbladder fossa shows normal gallbladder (GB) containing gall stones and sludge. Figure 2: Axial scan through right upper quadrant shows another cystic structure adjacent to the normal gall bladder that does not communicate with GB. Figure 3A and 3B: CT scan sagittal and coronal sections show two separate cystic structures in gallbladder fossa. Superior and anteriorly placed normal gallbladder (*) and the duplicated gall bladder posteroinferior in position to the normal gallbladder (arrow). Figure 4A and 4B: Axial section of epigastric region demonstrate possibility of two separate cystic ducts. Figure 4A shows the normal gall bladder and its cystic duct (arrow) and figure 4B depicts the duplicated gallbladder and the cystic duct (arrow head).


Diagnosis:

Duplicated Gallbladder


Discussion:

Duplication of the gallbladder is a rare congenital anomaly and thought to be due to an exuberant budding of the developing biliary tree with formation of two or more rudimentary gallbladders or due to failure of normal recanalisation of the gallbladder following solid stage of development [1]. Edward Boyden (1926) identified several types of duplicated gallbladder such as bilobed or bifid gallbladder which is considered as an incomplete variety and it is due to division of gallbladder by a septum or a diverticulum arising from part of the gallbladder [2,3]. Complete or the true duplication of gallbladder that does not communicate with each other and has two separate cystic ducts. The two cystic ducts can enter the common bile duct separately and form a H shape configuration (ductular type), or the Y shape where the two ducts unites to form a common origin. In ductular type one duct may open into intrahepatic ducts and part of the duplication can be intrahepatic [2,3]. Most of the duplicated gallbladder gives a clinical picture similar to other gall bladder diseases such as biliary colic, cholecystitis, obstructive jaundice and pancreatitis [4]. Complications of double gall bladder include torsion, papilloma, carcinoma, common duct obstruction and biliary cirrhosis. Grey scale ultrasound scan depicts two separate gallbladders as two separate cystic structures although demonstration of ductal anatomy or the type of duplication is not possible. Several conditions can mimic duplication of gallbladder, such as a folded gallbladder, bilobed gallbladder, choledochal cyst, pericholecystic fluid, gallbladder diverticulum, vascular band across the gallbladder and focal Adenomyomatosis [5]. Oral Cholecystogram demonstrate filling of contrast into two separate gallbladders and two separate cystic ducts. Opacification of two ducts can be enhanced by contraction of gallbladder after a fatty meal. Confusion occurs in cases where one gallbladder is involved with pathology where the normal gallbladder would be demonstrated and the abnormal gallbladder would not be outlined with contrast [2, 3]. Ductal anatomy is better defined by Endoscopic retrograde cholagiopanceatography ( ERCP), CT cholangiography and contrast enhanced MRCP (MR cholangiopancreatography) with mangafodipir trisodium. ERPC is considered the gold standard study in defining ductal anatomy. CT cholangiography had shown to be more useful in demonstrating ductal anatomy due to its higher spatial resolution compared to MRCP [5].


References / Suggested Reading:

1: Guyer PB, MRCP, FFR. McLaughlin M, MRCP, FFR: Congenital double gallbladder, A rewieve and report of two cases; 1967, Br J. Radiol, 40, 214-219. 2: Mackie DB, FRCS. Diagnosis and treatment of the duplication of gallbladder: Postgrad Med J,1966. 42, 213. 3: Williams JL, FRCS: A double gall bladder demonstrated by operative cholangigraphy; Postgrad Med J 1957 33: 236-238. 4: Mann CD, MRCS,BSc. Briggs CD, MRCS. Rajesh A, FRCR, et al: Defining ductal anatomy using CT cholangiography in a patient with gallbladder duplication. British journal of radiology, sep 2009, e175-177 5: Goiney RC. Schoenecker SA. Cyr DR et al: Sonography of gallbladder duplication and differential concideration; AJR 145; 241-243. 1985.


Author

Eranga Perera, Shweta Bhatt,MD, Vikram S Dogra,MD.

Research assistant

University of Rochester.