Hyperdense Basilar Artery

Images

Hyperdense Basilar Artery

Acute Infarcts in posterior circulation on DWI

Occlusion of Basilar on 3D TOF source image

Occlusion of Basilar artery


Clinical History:

A 63 year old right-hand-dominant diabetic woman with acute onset of nausea, vomiting, and slurred speech that progressed to loss of consciousness presented to the casualty department within half an hour of symptoms.


Findings:

FINDINGS NECT demonstrates a hyperdense basilar artery. This finding was evaluated by MRI brain with 3D Time of flight (TOF) angiography within 5 minutes of the CT. MR brain revealed no abnormality on T1, T2 and FLAIR images. The diffusion weighted sequence revealed restricted diffusion in the pons, cerebellum and the posterior cerebral arterial territories on both sides (Figure 2). Three dimensional TOF MR angiography (Figures 3 & 4) confirmed basilar artery thrombosis.


Diagnosis:

Top of Basilar Syndrome / Hyperdense Basilar artery/ Basilar artery occlusion


Discussion:

Acute thrombosis of the basilar artery either due to primary atheromatous disease in the vessel or from an embolus is a devastating neurological event. The diagnosis of this condition has to be early enough for planning direct therapeutic interventions or for expediting supportive care. Non enhanced computed tomographic scans may show a hyperdense basilar artery (HDBA) sign before a brainstem infarct is visualized. This sign should assist stroke team in diagnosis of basilar artery thrombosis. This holds true especially in the patients with signs of posterior circulation abnormalities.1 In the anterior circulation detection of “hyperdense middle cerebral artery (MCA) sign” has a high specificity for MCA occlusion. The application of similar sign in the posterior circulation is difficult due to inherent limitations of CT in evaluating posterior fossa and lack of conclusive evidence in applying HDBA sign for basilar thrombosis. Isolated studies have shown the benefit of using this sign in suspected cases of brainstem infarction. 1, 2 The pitfalls of CT like beam hardening artefacts in the posterior fossa and dual helical CT of posterior fossa may make the use of this sign unreliable.3 The identification of acute basilar thrombosis early may prompt interventional therapies like direct intra-arterial thrombolysis or mechanical clot retrieval and stenting of vertebral artery dissection when present. The presence of HDBA sign should at least prompt a emergency MR brain +/- MR angiography or a CT angiography of the brain to exclude basilar thrombosis as in the present case.


References / Suggested Reading:

1. Goldmakher GV, Camargo ECS, Furie KL et al. Hyperdense Basilar Artery Sign on Unenhanced CT Predicts Thrombus and Outcome in Acute Posterior Circulation Stroke. Stroke. 2009;40:134-139 2. Ehsan T, Hayat G, Malkoff MD et al. Hyperdense basilar artery. An early computed tomography sign of thrombosis. J Neuroimaging. 1994; 4:200-5. 3. Tomczak R, Traub U, Görich J, Brambs HJ. Double-helical CT pitfall: the native hyperdense basilar artery. Rontgenpraxis. 2000; 52(10-12):344-6.


Author

Paresh Desai

Goa University, Goa Medical College